- Artificial Intelligence Approach Helps Identify Type 2 Diabetes Risk
- How to Use Artificial Intelligence for Chronic Disease Management
The study authors note that previous research in this area has shown that ECGs can provide early insights into the presence of pre-diabetes and diabetes sooner, before other clinical signs related to blood glucose and hemoglobin. ECG-based methods are also less invasive than standard diagnostics for the two conditions, which could improve accessibility of diabetes screening if clinically validated, the researchers state.
For this study, families with at least one known case of type 2 diabetes were enrolled. Participants were asked to provide their personal and family medical histories, along with details about their diet, prior to any testing. Then, all participants underwent a range of blood tests and clinical assessments to help detect pre-diabetes and diabetes using American Diabetes Association criteria.
Just over 1,200 people were included in the study, and each had a standard ECG performed as part of their clinical assessment. From these, 100 structural and functional features from each lead were used to generate the predictors for the algorithm used in the study, known as DiaBeats.
Over 10,000 heartbeats were recorded from participants, which were split into training, validation, and independent test sets. The algorithm was tasked with classifying each participant as “no diabetes,” pre-diabetes, or type 2 diabetes based on ECG inputs.
Overall, diabetes prevalence in the cohort was high: 14 percent had pre-diabetes and 30 percent had type 2 diabetes. The ML algorithm achieved high performance in accurately identifying these participants, detecting the presence of the two conditions with accuracy and precision of 97 percent, independent of other factors like age, gender, and other metabolic disorders.
These findings, according to the researchers, indicate that their model may provide a more accessible alternative to current diabetes diagnostic methods to detect these diseases earlier, if clinically validated.
Other AI methods have also been used to stratify diabetes risk.
In April, researchers from the National Institutes of Health (NIH) Clinical Center developed a model capable of detecting type 2 diabetes risk using CT images that showed factors related to pancreatic health and fat levels.
AI has also been used to improve diabetes management, as shown in 2019 research from the Rensselaer Polytechnic Institute. As part of the research, information from thousands of continuous glucose monitors and insulin pumps were collected and evaluated based on performance and how often faults occur. These insights would then be used to improve the devices.
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